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High-Sensitivity Nucleic Acid Screening for SARS-CoV-2 Solutions for Pooled Sample Testing

 Pooled Sample Testing  of  SARS-CoV-2 

Product Overview

Background

As the global number of COVID-19 cases continues to increase, the world is facing a serious shortage of testing for SARS-CoV-2. WHO stressed that the capacity to detect SARS-CoV-2 should be rapidly enhanced to improve early diagnosis of COVID-19 pneumonia.

 

Pooled Sample Testing of SARS-CoV-2 

Currently there are two ways to perform sample pooling for SARS-CoV-2 testing: 1. Multi-sample pooling, which requires pooling the swab samples from multiple individuals into one collection tube and removing a specific volume from the tube for nucleic acid extraction; 2. Multi-sample mixing and extracting, which refers to collecting of individual’s samples to separate collection tubes, and then removing of equal volume of preservation solution from each tube  for the nucleic acid extraction. At present, the main problems of pooled sample testing are the lack of high-throughput nucleic acid extraction products for mass screening, and the limited sensitivity of the reagents which can easily lead to false negative results after the sample pooling.

Pooled sample testing can significantly improve testing efficiency and reduce testing costs. The Lancet, JAMA, PLoS One, Pathology and other journals have published studies confirming the feasibility and reliability of pooled sample testing for SARS-CoV-2 and recommending it for mass screening. China, the United States, South Korea and Germany have adopted pooled sample screening testing for SARS-CoV-2 for large populations, and have issued corresponding policies and technical guidelines successively.

 

Tianlong High-Sensitivity Solutions for Pooled Sample Testing

Based on years of technical experience and relevant authoritative guidelines, Tianlong has launched various solutions for pooled sample testing for SARS-CoV-2, including series of products for sample collection, nucleic acid extraction and nucleic acid detection, etc., with high extraction efficiency and low detection costs, ensuring the original or higher level of sensitivity, designed for rapid screening of large numbers of samples.

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Detection Process

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Clinical Significance

●  Comprehensive and accurate screening for potential risks.

●  Providing guidance for early detection and diagnosis for COVID-19 cases.

 

Advantages of Tianlong Solution

●  Full-Process Automated System:

Tube uncapping, sample loading and nucleic acid extraction can be automated completely for real minimized human interaction and risks of infection.

●  Large-Volume, High-Sensitivity:

Capable of extraction from large-volume samples up to 1000μL, with the sensitivity up to 20 copies/mL.

● High-Throughput, Low-Cost:

Testing for tens of thousands of samples per day can be easily completed, with high efficiency and low costs.

●  Accurate and Reliable:

The high-performing authoritative NMPA/CE-certified products have shown excellence in the wide applications of the clients and have received exceptionally good reviews by the customers.

● Various Solutions:

We provide a variety of sampling and extraction methods and combination options, with multiple models available.

 

Application Scenario

●  Overall Mass Screening for COVID-19 of the Entire Province/City

●  Mass Screening for Social Groups/Units

(Schools, Nursing Homes, Enterprises, Etc.)

●  Screening for Border and Port Inspection

(Travellers Arriving, Import Quarantine)

● Food Safety Inspection


High-Sensitivity Nucleic Acid Screening for SARS-CoV-2 Solutions for Pooled Sample TestingHigh-Sensitivity Nucleic Acid Screening for SARS-CoV-2 Solutions for Pooled Sample Testing.pdf


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