Human HLA-B*5801 Gene PCR Detection Kit

- Human HLA-B*5801 Gene PCR Detection Kit
  
  Human Leukocyte Antigens (HLA) play a key role in the development of severe immune-mediated adverse drug reactions. Multiple phenotypically distinct immune-mediated adverse drug reactions have been associated in particular with the carriage of specific HLA class I risk alleles.
  People with the genetic marker HLA-B*1502 have a much higher risk of severe drug eruption and exfoliative dermatitis (SJS/TEN) taking carbamazepine. Therefore, by detecting whether the HLA-B*1502 allele is carried, the risk of SJS/TEN induced by allopurinol in patients can be reduced.For Asians, especially the Han people, HLA-B*5801 is highly related to an allergy to allopurinol, a commonly used drug for the treatment of gout and hyperuric acid. Individuals with the genetic marker HLA-B*5801 have a much higher risk of blindness, death, and Stevenson-Jonson syndrome after taking this drug. Therefore, testing whether the HLA-B*5801 allele is carried can reduce the risk of SJS/TEN induced by allopurinol in patients.
  The Tianlong Human HLA-B*5801 Gene Nucleic Acid Detection Kit is intended for the qualitative detection of the human HLA-B*5801 gene nucleic acid by Real-time Polymerase Chain Reaction (Real-time PCR) method. It can detect the human HLA-B*5801 gene in the genomic DNA of human peripheral blood samples.

Product Manual

Product MSDS

Quote

Wide Coverage: Reliable detection of Human HLA-B*5801 Gene in exon 2 and exon 3
High Sensitivity: The limit of detection is up to 1ng/μL
Internal Control: The use of internal control system in the kit can effectively prevent false negative results
High Precision: The precision values of intra and inter Ct values are all ≤5%
User-friendly: Widely applicable in instruments with FAM, HEX/VIC, Cy5 fluorescence channels
More Accessible: CE marked, accessible for more counties

Specifications

Product Name	Human HLA-B*5801 Gene Nucleic Acid Detection Kit (Fluorescence PCR Method)
Cat.No	P127H
Specification	25T/Kit
Specimen	Peripheral blood
Target Gene	Human HLA-B*5801 Gene
Sensitivity	1ng/μL
Precision	≤5%
Storage & Validity	-25℃~-15℃ for 12 months
Applicable Equipment	Instruments with FAM, HEX/VIC, Texas Red fluorescence channels such as Applied Biosystemsmm 7500 Real-Time PCR Systems, Tianlong Gentier Real-time PCR Systems

Human HLA-B*5801 Gene Nucleic Acid Detection Kit (Fluorescence PCR Method)
Cat.No	P127H
Specification	25T/Kit
Specimen	Peripheral blood
Target Gene	Human HLA-B*5801 Gene
Sensitivity	1ng/μL
Precision	≤5%
Storage & Validity	-25℃~-15℃ for 12 months
Applicable Equipment	Instruments with FAM, HEX/VIC, Texas Red fluorescence channels such as Applied Biosystemsmm 7500 Real-Time PCR Systems, Tianlong Gentier Real-time PCR Systems