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  ["title"] => string(47) "Aspirin Resistance Testing: Reasons and Methods"
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  ["content"] => string(9827) "<p>Aspirin is widely considered the best practice for antiplatelet therapy in cardiovascular diseases (CVD)&nbsp;management. It is&nbsp;a&nbsp;cornerstone in preventing myocardial infarction by inhibiting platelets from forming blood clots. &nbsp;</p><p>However, the prevalence of aspirin resistance differs greatly across various groups of people based on factors&nbsp;such as&nbsp;gender, age, underlying health conditions, and <a href="https://www.medtl.net/products/aspirin-personalized-medication-solutions.html" target="_self">aspirin resistance testing</a>&nbsp;methodologies.</p><p>A systematic review found that aspirin resistance could be higher in women (26.9%) than men (23.5%)[1], and elderly patients with coronary artery disease had 9.3% to 24.8% aspirin resistance[1].</p><p>These findings underscore the need for accurate aspirin resistance testing to enhance personalized medicine and improve patient outcomes.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241031/1730352081636463.png" title="" alt="1.png"/></p><p></p><p><strong>How Does Aspirin Inhibit Platelet Aggregation?</strong> </p><p>Aspirin, also known as acetylsalicylic acid, stops platelets from sticking together and forming clots by irreversibly blocking the enzyme cyclooxygenase (COX-1). Platelets need this enzyme to make thromboxane A2, a potent platelet activator, which induces platelet aggregation.</p><p>Without thromboxane A2, platelets can&#39;t clump together to&nbsp;form harmful blood clots. Moreover, they have no nucleus and DNA, so no new COX-1 can be produced. Hence, the effect of aspirin on platelets persists until new platelets are made, which takes about 7 to 10 days.</p><p>Even after stopping aspirin, the&nbsp;body may still take some time to resume&nbsp;normal blood clotting. Aspirin also changes a specific enzyme called COX-2. It is required in the prostaglandin pathway to reduce inflammation in the body. This is how aspirin helps decrease pain and swelling when taken in higher doses.</p><p><strong>Mechanisms Behind Aspirin Resistance and Its Clinical Consequences</strong> </p><p>However, this drug can fail to hit its pharmacological target (COX-1), not effectively inhibiting platelet function and clot formation in a certain kind of group. In clinics, it is known as aspirin resistance.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241031/1730352126721654.png" title="" alt="2.png"/></p><p></p><p style="text-align: center;"><em><span style="font-size: 12px;">(Copyright photo from: https://en.wikipedia.org/wiki/File:Blood_clot_diagram.png)</span></em></p><p><strong>1.&nbsp;Mechanisms&nbsp;of Aspirin Resistance</strong></p><p>To optimize patient management, it&#39;s important to understand these mechanisms. Various reasons could cause the occurrence of aspirin resistance, including:</p><p></p><ul style="list-style-type: disc;"><li><p><strong>Reduced Bioavailability</strong> </p></li></ul><p>Aspirin works best when it is absorbed well in the stomach. Factors like pH level and meal intake can affect its absorption rate. Variability in absorption can result in varying plasma concentration levels, which might make it less effective.</p><ul style="list-style-type: disc;"><li><p><strong>Increased Platelet Turnover</strong></p></li></ul><p>In some inflammatory processes, such as atherosclerosis and other complications, the body makes new platelets faster than normal. This reduces aspirin&#39;s ability to block COX-1, which results in less efficacy of the drug over time.</p><ul style="list-style-type: disc;"><li><p><strong>Negative Drug Interactions</strong></p></li></ul><p>Taking&nbsp;other drugs such as&nbsp;NSAIDs (non-steroidal anti-inflammatory drugs) along with aspirin can interfere with its&nbsp;binding&nbsp;to&nbsp;COX-1, diminishing&nbsp;its effectiveness in&nbsp;preventing&nbsp;blood clots.</p><p><strong>2.&nbsp;Clinical Consequences of Aspirin Resistance</strong></p><p>A research study has shown that aspirin resistance can raise heart events to 13 times higher in cardiovascular patients[2]. Generally, &nbsp;factors can result in severe clinical consequences:</p><ul style="list-style-type: disc;"><li><p>High risk of myocardial infarction and stroke</p></li><li><p>Alternative antiplatelet agents</p></li><li><p>Difficulty in patient management</p></li><li><p>Need for precise aspirin resistance testing</p></li></ul><p><strong>Methods of Aspirin Resistance Testing</strong></p><p>Accurate&nbsp;aspirin resistance testing&nbsp;is essential for&nbsp;optimizing&nbsp;patient outcomes, as it enables&nbsp;healthcare professionals to personalize&nbsp;aspirin&nbsp;therapy. The following aspirin resistance testing methods are widely used to check its&nbsp;effectiveness:</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241031/1730352173340488.png" title="" alt="3.png"/></p><p></p><p style="text-align: center;"><span style="font-size: 12px;"><em>(Copyright photo from: https://unsplash.com/photos/red-plastic-container-with-white-powder-kQrBavaF-Fk)</em></span></p><p><strong>1.&nbsp;Platelet Function Tests</strong></p><p>Platelet function test is one of the methods to undergo aspirin resistance testing in labs and clinical settings, such as:</p><ul style="list-style-type: disc;"><li><p>Light Transmission Aggregometry (LTA)</p></li><li><p>Platelet Function Analyzer 100/200 (PFA 100/200)</p></li><li><p>Thromboelastography (TEG)</p></li><li><p>Thromboxane B2&nbsp;(TXB2) Testing &nbsp;</p></li></ul><p>These aspirin resistance tests can be used to measure the efficacy of aspirin in preventing platelet aggregation. However, in a study of 201 patients with stable coronary artery disease, researchers found unclear results in these different tests[3]. Yield significantly varied results when detecting aspirin resistance. It suggests that these tests may not reliably assess aspirin&#39;s antiplatelet effects.</p><p>Besides, &nbsp;the study found poor correlation and agreement among the different testing methods as well[3]. This indicates that even when multiple aspirin resistance tests are employed, the conclusions might be inconsistent, complicating clinical decision-making.</p><p><strong>2.&nbsp;Genetic Tests</strong></p><p>Genetic testing for aspirin resistance is an emerging area of research that aims to enhance the effectiveness of aspirin therapy in preventing cardiovascular diseases. Several studies have identified specific genetic variants associated with aspirin resistance, notably including[4]:</p><ul style="list-style-type: disc;"><li><p>ITGB3</p></li><li><p>ITGA2</p></li><li><p>PTGS1</p></li><li><p>PTGS2</p></li></ul><p>Similarly, a study reviewed various laboratory genetic tests for aspirin resistance, showing&nbsp;a strong link between the particular genetic variant “P1A1/A2” in the GPIIIa receptor gene (ITGB3) and aspirin resistance[5].</p><p>Consequently, genetic testing is a more reliable way to&nbsp;identify patients likely to benefit from alternative therapies or adjusted dosages, thereby improving precision medicine&nbsp;and treatment outcomes</p><p><strong>Tianlong’s Aspirin Personalized Medication Solutions</strong></p><p>This association is&nbsp;especially noted in healthy individuals, but it&nbsp;can only be identified&nbsp;if the results are accurate. To ensure&nbsp;error-free results, Tialong’s <a href="https://www.medtl.net/products/reagents/ligation-sequencing-kits-precision-medicine" target="_self">ligation sequencing kit</a>, the Aspirin Personalized Medication Solution, is specifically designed for precision in aspirin resistance testing and subsequent&nbsp;medication use. The features include:</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241031/1730352272828666.png" title="" alt="4.png"/></p><p></p><ul style="list-style-type: disc;"><li><p>99% accuracy in detection results</p></li><li><p>70 minutes process to determine the presence of TGB3 (c.176 T&gt;C), LTC4S (c.-444 A&gt;C), PEAR1 (C.-9-3996 G&gt;A), PTGS1 (c.-842 A&gt;G) and GP1BA (c.482 C&gt;T)&nbsp;</p></li><li><p>Pre-filled reagents without sample extraction</p></li></ul><p><strong>Conclusion</strong></p><p>Aspirin resistance poses&nbsp;a significant&nbsp;challenge for cardiovascular patients. Accurate aspirin resistance testing methods are required for precision medicine. Using accurate and efficient testing reagents like Tianlong’s ligation sequencing kits on aspirin resistance, doctors can offer customized treatments for better safety and aspirin efficacy.</p><p>At Tianlong, we are a trusted&nbsp;name in genetic testing and molecular diagnostics. With 100+ independent intellectual property rights and 200 international certifications, our solutions have made significant&nbsp;contributions to disease prevention and control. For any inquiries or further&nbsp;information, please feel free to contact us directly.</p><p><strong>Reference</strong></p><p>[1]&nbsp;Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7265510/</p><p>[2]&nbsp;Available at: https://pubmed.ncbi.nlm.nih.gov/18766252/</p><p>[3]&nbsp;Available at: https://academic.oup.com/eurheartj/article/28/14/1702/2887650</p><p>[4]&nbsp;Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC10014202/</p><p>[5]&nbsp;Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC2492913/</p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p><br/></p>"
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  ["title"] => string(15) "Happy Halloween"
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  ["content"] => string(593) "<p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241031/1730351778104117.jpg" title="" alt="微信图片_20241028111717.jpg" width="401" height="535" style="width: 401px; height: auto;"/></p><p>Happy #Halloween! This spooky season, let’s unlock the mystery of health together!</p><p>With our trusted diagnostic solutions, you can rest easy knowing that whether it’s #Biochemical, #Immunology, #Molecular, or #Point-of-Care Diagnostics, we have the tools to clear up any uncertainties in your results!</p><p></p><p></p><p><br/></p>"
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  ["title"] => string(46) "Tianlong to be Participating in the Medica2024"
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  ["content"] => string(2161) "<p>We are excited to announce that Tianlong&nbsp;will be participating in the upcoming Medica2024&nbsp;exhibition in Düsseldorf, Germany with KHB&nbsp;and TechnogeneticsS.r.l. (TGS). This is one of the world&#39;s largest medical trade fairs, showcasing the latest innovations&nbsp;and advancements in healthcare.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241028/1730107166409910.jpg" title="" alt="德国展会海报-07(1).jpg" width="443" height="591" style="width: 443px; height: auto;"/></p><p><strong>Mark the calendar!</strong></p><p>Event: MEDICA 2024</p><p>Booth: #1B45</p><p>Dates: 11 - 14 November</p><p>Venue: Messe Düsseldorf, #Germany</p><p>&nbsp;</p><p>We warmly invite you to visit our booth to explore our cutting-edge #diagnostic solutions and learn more about our latest products in #biochemistry, #immunology, #POCT, #molecular&nbsp;diagnostics, and more at this prestigious medical event. Join us on-site to experience hands-on demonstrations of&nbsp;our innovations!</p><p><a href="https://www.medtl.net/products/solution/all-in-one-molecular-diagnosis-systems/all-in-one-molecular-diagnosis/254.html" target="_self">Panall 8000 All-in-one Molecular Diagnosis system (Open system)</a></p><p><a href="https://www.medtl.net/products/gentier-x3-series-real-time-pcr-system.html" target="_self">Gentier X3 Series Real-Time PCR System</a></p><p><a href="https://www.medtl.net/products/biolum-portable-atp-monitoring-system-pro.html" target="_self">Biolum Portable ATP Hygiene Monitoring System Pro</a></p><p><a href="https://www.skhb.com/en/product/newdetail_3736.html" target="_self">Automatic Chemiluminescence Immunoassay Analyzer V150</a></p><p><a href="https://www.skhb.com/en/product/newdetail_2671.html" target="_self">Automatic Clinical Chemistry Analyzer ZY-260</a></p><p><br/></p><p>This is a fantastic opportunity to meet our team, discuss collaboration possibilities, and discover&nbsp;how our innovations can support your needs. If you’re interested, feel free to message us&nbsp;directly or email us at inquiry@medtl.com to schedule an in-person meeting!</p>"
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  ["title"] => string(63) "An Ultimate Solution for Diagnosing Feline Respiratory Distress"
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  ["content"] => string(11025) "<p>Just as is the case with humans, cats may become vulnerable to respiratory diseases within a short time. These illnesses begin gradually to interfere with the breathing ability of a cat, thereby affecting its general well-being. If left without treatment, a cat becomes subjected to severe instances of breathing complications, which makes it hard for the cat to eat or even play. Chronic illness, pain, and even death occur over time. But what if there existed an easy way of early diagnosis of such <a href="https://www.medtl.net/products/feline-respiratory-5-types-pathogen-panel-nucleic-acid-detection-kit-fluorescence-pcr-method.html" target="_self">feline respiratory distress</a>?</p><p style="text-align: center;">&nbsp;<img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149786211430.png" title="" alt="aa.png"/></p><p style="text-align: center;"><em><span style="font-size: 12px;">(Copyright image from: https://www.freepik.com/free-photo/medium-shot-elderly-man-with-cat_37558871.htm#fromView=search&amp;page=1&amp;position=15&amp;uuid=816ee95a-eef6-477e-ac7c-e222b996f8fb)</span></em></p><p><strong>Why Cats Are Susceptible to Respiratory Diseases?</strong></p><p>Cats are prone to feline respiratory distress infections. It often happens this way because cats will find each other at animal shelters, homes, or outdoors. Such diseases are caused by pathogens, like viruses and bacteria. Once the pathology has affected a cat&#39;s respiratory system, it normally demonstrates symptoms characterized by sneezing, coughing, nasal discharge, and difficulty breathing. Such clinical signs are elements of the feline respiratory disease complex&nbsp;and can make a cat feel pretty ill and affect its overall rate of respiration.&nbsp;These cats need to be diagnosed in time and get the proper treatment. Therefore, a reliable tool that identifies typical pathogens responsible for such diseases will be helpful.</p><p></p><p><strong>Common Causes of Respiratory Infections in Cats</strong></p><p>There are several pathogens responsible for feline respiratory disease&nbsp;complex symptoms. However, the most common ones are:</p><p><strong>1.&nbsp;Feline Herpesvirus (FHV-1)</strong></p><p>This is one of the critical causes of feline respiratory distress. Its symptoms include sneezing, eye discharge, and nasal congestion. The FHV-1 virus is very contagious since once a cat is infected, it carries it its whole life. Thus, at times of stress, the virus may reactivate and cause new diseases.</p><p><strong>2.&nbsp;Feline Calicivirus (FCV)</strong></p><p>FCV is another contagious virus that affects the respiratory system and can cause oral diseases. It often co-occurs with FHV-1 and is responsible for many upper respiratory infections (URIs) in cats.&nbsp;Symptoms include sneezing, nasal discharge, ulcers in the mouth (especially on the tongue and gums), drooling, fever, and joint pain. Some strains of FCV can cause severe respiratory distress.</p><p><strong>3.&nbsp;Bordetella bronchiseptica (Bb)</strong></p><p>Bordetella bronchiseptica is a bacterial pathogen that commonly causes respiratory infections in dogs but can also infect cats. It’s especially prevalent in high-density environments like shelters and catteries.&nbsp;While it typically causes mild symptoms, it can be more dangerous in kittens, older cats, or those with weakened immune systems.</p><p><strong>4.&nbsp;Mycoplasma Felis (MF)</strong></p><p>Mycoplasma felis is a type of bacteria that lacks a cell wall, making it unique from other bacteria. It can infect the respiratory system, as well as the eyes, causing respiratory infections and conjunctivitis.&nbsp;Mycoplasma infections can be chronic and challenging to treat, particularly when combined with other feline respiratory distress. In some cases, it can lead to pneumonia.</p><p><strong>5.&nbsp;Chlamydophila Felis (CF)</strong></p><p>This bacterium mainly causes conjunctivitis&nbsp;and&nbsp;cat eye infections and can be cat-to-cat transmitted through direct contact. CF infection is mainly observed in cats that share their environments, for instance, those staying in a cattery or a shelter.&nbsp;This bacterium spreads through direct contact with infected cats, mainly through eye secretions. It can also be spread via contaminated objects like bedding or food bowls.</p><p>These five pathogens are the main causes of feline respiratory distress. Early determination of the appropriate pathogen will mean providing the cat with the correct treatment for its condition, improving the cat&#39;s health.</p><p><strong>Diagnostic Techniques for Feline Respiratory Distress</strong></p><p>Diagnosis of a feline showing signs of respiratory distress is made based on various methods by which veterinarians identify the cause of distress. These diagnostic techniques commonly include:</p><p><strong>1.&nbsp;Serological Testing</strong></p><p>This is an in-blood testing technique whereby one checks whether there are antibodies or antigens in the blood of a cat associated with particular disease-causing pathogens.&nbsp;Serological testing is often employed when veterinarians suspect viral or bacterial infections and want to confirm a diagnosis based on immune response, particularly when combined with clinical symptoms.</p><p><strong>2.&nbsp;Radiography and Imaging Techniques</strong></p><p>X-rays or other imaging techniques are often available so the veterinarian can see through the body to see the lungs and chest area; changes in form,&nbsp;such as fluid buildup or signs of inflammation,&nbsp;may indicate a respiratory disease.&nbsp;Radiography is commonly used to assess the severity of respiratory distress, particularly when secondary complications like pneumonia, bronchitis, or pleural effusion are suspected.</p><p><strong>3.&nbsp;PCR Testing</strong></p><p>One of the most reliable methods adopted in detecting pathogens is Polymerase Chain Reaction or PCR testing. This technique can indicate the existence of particular genetic material coming from either bacteria or viruses. This would thus give an accurate and rapid diagnosis. This technique has been of great importance in the detection of respiratory infections caused by multiple pathogens.</p><p style="text-align: center;">&nbsp;<img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149877136136.png" title="" alt="bb.png"/></p><p style="text-align: center;"><span style="font-size: 12px;">(Copyright image from: https://www.freepik.com/free-photo/white-fluffy-cat-veterinarian-with-cats-animals-couch_13320879.htm#fromView=search&amp;page=1&amp;position=0&amp;uuid=9b9b21b7-b248-4612-b635-001fbb3548bb)</span></p><p></p><p><a href="https://www.medtl.net/products/feline-respiratory-5-types-pathogen-panel-nucleic-acid-detection-kit-fluorescence-pcr-method.html" target="_self"><strong>TIANLONG&#39;s Feline Respiratory 5 Types Pathogen Panel Kit:</strong></a><strong>&nbsp;An Efficient and Effective Diagnostic Solution</strong></p><p></p><p></p><p></p><p></p><p></p><p>For anyone looking for the most accurate and efficient diagnostic tool, a perfect solution can be found in TIANLONG&#39;s Feline Respiratory 5 Types Pathogen Panel Nucleic Acid Detection Kit (Fluorescence PCR Method). Here are some reasons why this freeze-dried nucleic acid kit is good for the diagnosis of feline respiratory diseases.</p><p><strong>·&nbsp;Accurate Detection</strong></p><p>With the advanced technology of PCR, this kit goes around detecting DNA or RNA of the five most common respiratory pathogens in cats, including Feline Herpesvirus, Feline Calicivirus, Bordetella bronchiseptica, Mycoplasma Felis, and Chlamydophila Felis. The fluorescence PCR method ensures high sensitivity and can easily detect the minute presence of genetic material of&nbsp;feline respiratory distress&nbsp;pathogen. This degree of accuracy helps veterinarians quickly determine what ails a cat.</p><p><strong>·&nbsp;Internal Control</strong></p><p>The kit comprises an internal control for the purification process and is free from contamination. This will provide confidence among users concerning the accuracy and dependability of the results.</p><p><strong>·&nbsp;Easy and Simple to Use</strong></p><p>TIANLONG&#39;s Feline Respiratory 5 Types Pathogen Panel Nucleic Acid Detection Kit is simple to use due to its property of freeze-dried. This reagent only requires reconstitution in water before use, reducing the number of preparation steps and potential for errors compared to traditional liquid PCR reagents. As a result, our Tianlong kit can be highly recommended for veterinary clinics, research labs, and animal shelters for treating feline respiratory distress.</p><p><strong>How Feline Respiratory 5 Types Pathogen Panel Nucleic Acid Detection Kit Works?</strong></p><p>It is quite easy to use&nbsp;TIANLONG&#39;s Feline Respiratory 5 Types Pathogen Panel Nucleic Acid Detection Kit. Here are the basic steps as follows:</p><p><strong>·&nbsp;Sample Collection</strong></p><p>Sample collection aims to collect a sample from the cat that may contain genetic material (DNA or RNA) of the pathogens causing the respiratory infection. The collected swabs are then placed in a transport medium to preserve any pathogens present until laboratory processing.</p><p><strong>·&nbsp;Nucleic Acid Extraction</strong></p><p>This step aims to isolate and purify the nucleic acids (DNA or RNA) from the pathogens present in the collected sample. This step is crucial because PCR requires pure nucleic acid to accurately amplify and detect specific pathogen sequences.</p><p><strong>·&nbsp;PCR Detection</strong></p><p>This step aims to detect the presence of specific pathogen genetic material by amplifying targeted sequences using real-time PCR. Fluorescence is used to quantify the amount of nucleic acid during the amplification process.&nbsp;The test results indicate the presence or absence of the five ordinary feline respiratory pathogens based on the fluorescence signal during PCR. If a pathogen’s genetic material is detected, the corresponding pathogen is identified as the cause of the respiratory distress.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149957778328.png" title="" alt="cc.png"/></p><p></p><p></p><p><strong>Conclusion</strong></p><p>Our TIANLONG’s&nbsp;Feline Respiratory 5 Types Pathogen Panel Nucleic Acid Detection Kit has been effective in the diagnosis of feline respiratory distress. As this diagnostic kit is accurate and user-friendly in its design, results acquired through it are reliable. This makes them ideal for veterinary clinics, any research laboratory&nbsp;that wants to lower the feline respiratory rate&nbsp;or even a pet owner who sincerely cares for his/her animals.</p><p>For more details on this product, as well as other diagnostic tools by TIANLONG, visit our&nbsp;entire lineup of diagnostic instruments.&nbsp;</p>"
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  ["title"] => string(71) "Food Safety Monitoring for Lab Researchers: Mission, Indicator & Method"
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  ["content"] => string(8627) "<p>Research labs play a critical role in ensuring food quality so that consumers can have a healthy eating environment. They use microbiological and chemical testing to determine whether the food contains microbes or pathogens. It is their utmost responsibility to maintain a healthy food supply chain by detecting hazards and meeting safety standards. This food safety monitoring&nbsp;helps reduce the risk of foodborne diseases and retrain consumer trust.</p><p>So, in today’s article, we are going to provide a detailed guide on how they carry out effective monitoring for high standards of the food, seeing what mission, indicator, and methods for food safety monitoring in labs.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149398747503.jpg" title="" alt="a.jpg"/></p><p></p><p><strong>The mission of Food Safety Monitoring in Lab</strong></p><p>The primary purpose of lab researchers in food safety monitoring is to ensure that all food products are safe to consume. It involves various detection methods, preventive measures, and expertise to check contamination.</p><p>So, the ultimate mission is to identify the risks before letting them reach the market, assessing the chemical and biological hazards in food during distribution. It includes knowledge of identification, detecting methods, analysis, monitoring, and extracting reports. Along with detecting hazards, labs also help in preventing contamination during food production.</p><p>Besides, they also ensure the whole process follows the set standards of food safety and regulations, like the FDA, EFSA, etc.</p><p>They also check and analyze previous statistics and reports to avoid future hazards and potential risks. The safe food standards are set by authorities.</p><p><strong>Key Indicators of Food Safety Monitoring</strong></p><p>Food safety monitoring or testing commonly examines food chemical composition, the presence of pathogens, physical properties, and the potential for unsafe ingredients. Lab researchers use specific measures to check the contamination or hazards in food. Here are the key indicators that determine how safe the food is for consumption.</p><p></p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149431571408.png" title="" alt="b.png"/></p><p><strong>Microorganisms in Food Safety Concerns</strong></p><p>Compared to other contaminations, microorganisms multiply, cause foul odor in the food, and show spoilage signs. Infections occur when you eat the contaminated food, and bacteria continue to multiply in your gastrointestinal system. It could render 128,000 hospitalized, and even 3,000 die every year in the United States.&nbsp;Patients always have the following symptoms:</p><ul style="list-style-type: disc;"><li><p>Fever</p></li><li><p>Nausea or Vomiting</p></li><li><p>Diarrhea &amp; Stomach Cramping</p></li></ul><p>As a result, undergoing food safety monitoring aims to find out the cause of foodborne illness. More importantly, it is a kind of social responsibility to ensure public health. &nbsp;</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149468666771.png" title="" alt="c.png"/></p><p></p><p><strong>Monitoring Tools for Microbicidal Indicators of Food Safety</strong></p><p>For food safety monitoring, there are tools that lab researchers use to detect and test microbicidal indicators. These help them have an estimation of the microbes and ATP count in the food. Here are the tools and their usage in food monitoring:</p><p><strong>1.&nbsp;Microscopy</strong></p><p>Food contamination is detected with various analysis methods because of safety reasons. For this analysis, the lab researchers use microscopy, a device to identify microorganisms in prepared food. It allows a direct look at bacteria, yeast, molds, and other contamination.</p><p>Different microscopes are used to identify different microbial contamination that are as follows:</p><p>·&nbsp;Stereo Microscopes: Used for spotting foreign materials in food at low magnification.</p><p>·&nbsp;Polarizing Microscope: Identifies microbes in fatty or fibrous foods.</p><p>·&nbsp;Fluorescence Microscope: Detects bacteria like Staphylococcus aureus and E. coli using gram staining.</p><p>·&nbsp;Scanning Electron Microscopes: Essential for examining high-fat or high-water foods and controlling moisture and pressure.</p><p><strong>2.&nbsp;Total Plate Count (TPC) and Aerobic Plate Count (APC)</strong></p><p>TPC is a method used to determine the total number of bacteria in a food sample, while APC is used as an indicator to tell the populations of bacteria in food samples. These serve as excellent indicators in food safety monitoring to determine the contamination and effectiveness of particles. Lab researchers use them for various stages in food production, from ingredients to the final product.</p><p><strong>3.&nbsp;ATP Monitoring System</strong></p><p>The ATP monitoring system is a device used to meet the ATP test standards of the given food sample. Because of the presence of ATP, these foods are more likely to be contaminated by microorganisms. When food is combined with chemicals in the sampler, a chemiluminescent reaction occurs that results in light. The amount of light decides how much ATP is present in the food.</p><p><strong>Introducing Tianlong’s Biolum Portable ATP Monitoring System Pro</strong></p><p>Our<a href="https://www.medtl.net/products/biolum-portable-atp-monitoring-system-pro.html" target="_self"> Tianlong’s Biolum Portable ATP Monitoring System Pro</a>&nbsp;is a powerful and convenient ATP testing solution that can deliver accurate food safety monitoring results in labs. The key features of Biolum Portable ATP Monitoring System Pro are as follows:</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729149550497805.png" title="" alt="d.png"/></p><p></p><ul style="list-style-type: disc;"><li><p><strong>Exceptional Sensitivity</strong></p></li></ul><p>Capable of detecting as little as 10-16&nbsp;mol of ATP, the Biolum Portable ATP Monitoring System Pro offers unparalleled accuracy in assessing surface cleanliness, ensuring the highest standards of hygiene.</p><ul style="list-style-type: disc;"><li><p><strong>Rapid Verification</strong></p></li></ul><p>The Biolum Portable ATP Monitoring System Pro delivers swift sanitation verification, with each test completed in just 10 seconds. This rapid testing capability ensures immediate feedback and efficient workflow in any setting.</p><ul style="list-style-type: disc;"><li><p><strong>Pre-configured Templates</strong></p></li></ul><p>To accommodate the diverse needs of different sectors and locations, the Biolum Portable ATP Monitoring System Pro comes equipped with an array of pre-configured templates. This feature simplifies the setup process and then undergoes immediate deployment across a variety of environments.</p><ul style="list-style-type: disc;"><li><p><strong>Compatible Lyophilized Surface Swab</strong></p></li></ul><p>Our ATP testing system is designed to work seamlessly with the ATP Lyophilized Surface Swab—a user-friendly and effective tool for collecting samples. This compatibility ensures that users can conduct thorough and reliable tests with minimal training.</p><ul style="list-style-type: disc;"><li><p><strong>Cloud-Based Data Management</strong></p></li></ul><p>With its sophisticated cloud-based platform, Tianlong’s Biolum Portable ATP Monitoring System Pro enables comprehensive data management. Users can effortlessly monitor, track, and analyze testing results from multiple facilities, enhancing the ability to manage risks and maintain compliance.</p><p></p><p><strong>Conclusion</strong></p><p>Food safety monitoring is essential for lab researchers. With the help of different tools and systems, they can fetch results for different food cleanliness purposes. Using the right tool enables researchers to have quicker and more accurate results, which makes handling various tests easy.</p><p>At Tianlong, we are an innovative R&amp;D company established in 1997 to provide testing instruments, products, and solutions. We have delivered our products in 100+ countries and regions and have 80+ NMPA approvals and 200 international certificates. As a result, you can trust our ATP testing device. If you are interested, please visit our Tianlong’s official website to learn more and contact us!</p>"
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  ["title"] => string(79) "Intl Infection Prevention Week | KHB&Tianlong Solution for Infectious Diseases "
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  ["content"] => string(2110) "<p>International Infection Prevention Week (#IIPW) is an event celebrated on the 3rd week of every year in October, aiming to improve awareness of the significance of #infection&nbsp;prevention.</p><p>This year 2024, #InternationalInfectionPreventionWeek&nbsp;is celebrated from 13th to 19th. On this week, Infection preventionists (IPs) from different countries and fields will join together to educate healthcare workers and patients about infection #prevention&nbsp;practices.</p><p style="text-align: center;"><strong><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241014/1728897683268267.png" title="" alt="IIPW-2024-Announcement-Twitter-X-Post-2.png" width="643" height="362" style="width: 643px; height: auto;"/></strong></p><p><strong>Importance of International Infection Prevention Week</strong></p><p>Infectious diseases can lead to #global&nbsp;pandemics when they spread rapidly. Infections in homes, workplaces or hospitals can affect people&#39;s&nbsp;#health&nbsp;and make it harder for healthcare workers to do their jobs.&nbsp;It’s time to...</p><ul style="list-style-type: disc;"><li><p>Promotes Awareness and Education</p></li><li><p>Prevents Healthcare-Associated Infections (#HAIs)</p></li><li><p>Supports Global Health Security</p></li><li><p>Encourages Innovation and Best Practices</p></li></ul><p><strong>KHB&amp;Tianlong Solution for Infectious Diseases</strong> </p><p>At KHB&amp;Tianlong, we offer comprehensive diagnostic solutions for various infectious diseases using advanced methodologies such as ELISA, CLIA, PCR&nbsp;and POCT. Our cutting-edge detection covers a wide range of infectious diseases, including viral hepatitis (HAV, HBV, HCV), sexually transmitted infections (HIV, syphilis, CT, NG), respiratory infections (influenza), gastrointestinal infections, tropical zoonotic diseases (Dengue, Zika), and herpes viruses (Mpox, VZV), among others.</p><p>We ensure fast, reliable, and accurate results to support better disease management and public health. Let us help you safeguard your health with our advanced detection technology!</p>"
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  ["title"] => string(78) "Tianlong Introduces Marburg Virus Detection Kit in Response to Rwanda Outbreak"
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  ["content"] => string(3837) "<p>On 27 September 2024, the Rwanda Ministry of Health announced the confirmation of Marburg virus disease (MVD). A&nbsp;total of 26 confirmed cases, including eight deaths (CFR: 31%), have been reported. Blood samples taken from people showing symptoms were tested by real-time reverse transcription polymerase chain reaction (RT-PCR) at the National Reference Laboratory of the Rwanda Biomedical Center and were positive for Marburg virus.</p><p style="text-align: center;"><strong><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241012/1728710998411573.jpg" title="" alt="微信图片_20241012102402 (1).jpg" width="695" height="927" style="width: 695px; height: auto;"/></strong></p><p><strong>About Marburg Virus Disease (MVD)</strong></p><p>Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever, is a severe, often fatal illness in humans.&nbsp;The average MVD case fatality rate is around 50%. Case fatality rates have varied from 24% to 88% in past outbreaks.&nbsp;There are currently no approved vaccines or antiviral treatments for MVD, but a range of vaccines and drug therapies are under development.</p><p><strong>Transmission of Marburg Virus</strong></p><p>Marburg virus can spread through human-to-human transmission via direct contact (through broken skin or mucous membranes) with the blood, secretions, organs or other bodily fluids of infected people, and with surfaces and materials (e.g. bedding, clothing) contaminated with these fluids.</p><p><strong>Symptoms of Marburg Virus Disease</strong></p><p>The incubation period (interval from infection to onset of symptoms) varies from 2 to 21 days.&nbsp;MVD begins abruptly, with high fever, severe headache and severe malaise. Muscle aches and pains are a common feature. From day 5 of the disease, patients may develop haemorrhagic manifestations, including fresh blood in vomitus and faeces, bleeding from the nose, gums, and vagina. In fatal cases, death occurs most often between 8 and 9 days after symptom onset, usually preceded by severe blood loss and shock.</p><p><strong>Diagnosis of MVD</strong></p><p>Diagnosing MVD can be challenging due to symptom overlap with other diseases like malaria, typhoid fever, and other viral haemorrhagic fevers. The confirmation of Marburg virus infection is made through diagnostic methods such as:</p><p>- Reverse transcriptase polymerase chain reaction (RT-PCR) assays &nbsp;</p><p>- Antibody-capture enzyme-linked immunosorbent assays (ELISA) &nbsp;</p><p>- Antigen-capture detection tests &nbsp;</p><p>- Virus isolation in maximum containment laboratories</p><p><strong>Tianlong Marburg Virus Nucleic Acid Detection Kit (Real-time RT-PCR)</strong> </p><p>In the absence of specific treatments or vaccines, early supportive care, including rehydration and symptomatic treatment, can improve survival rates.</p><p>To assist in the diagnosis and public health response to Marburg virus disease, Tianlong has developed the <a href="https://www.medtl.net/products/marburg-virus-nucleic-acid-detection-kit-fluorescence-pcr-method-p696h.html" target="_self">Marburg Virus Nucleic Acid Detection Kit</a>, based on the qualitative detection of Marburg Virus nucleic acid by Real-time reverse transcription Polymerase Chain Reaction (real-time RT-PCR) method. This kit is&nbsp;designed to detect RNA from Marburg Virus in specimens such as human serum sample collected from individual personnel based on clinical and/or epidemiological criteria,&nbsp;facilitating early diagnosis and effective disease management.</p><p>By providing fast and precise detection,<a href="https://www.medtl.net/" target="_self"> Tianlong&#39;s solution</a>&nbsp;supports clinical decisions, aiding in both the care of individual patients and the overall public health response to MVD outbreaks.</p>"
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  ["title"] => string(56) "ATP Monitoring: Why Is It Important for Food Safety Lab?"
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  ["content"] => string(8961) "<p>Ensuring food safety&nbsp;should be the utmost priority of every food industry professional. A single lapse in hygiene can lead to significant health issues. According to a report by WHO, almost&nbsp;420,000 people die every year by eating contaminated food<sup>[1]</sup>.</p><p>ATP Labs guarantee new cleanliness standards by testing germs and organic residues on surfaces. In a&nbsp;food safety lab, ATP testing gadgets are used as critical markers for unhygienic surfaces.</p><p>Below, we have shared how <a href="https://www.medtl.net/products/biolum-portable-atp-monitoring-system-pro.html" target="_self">ATP monitoring</a>&nbsp;devices have revolutionized cleanliness standards in food safety labs.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241011/1728617763388982.png" title="" alt="1.png"/></p><p>&nbsp;</p><p><strong>ATP, Explained</strong></p><p>ATP (Adenosine Triphosphate) is an organic molecule in the cell membranes of living organisms. Often termed the &quot;energy source&quot; of cells, it is a nucleotide helping the human body in various functions. Mostly, it is used during muscle contraction, nerve impulse propagation, and chemical synthesis. An enzyme ATP synthase produces ATP in cells<sup>[2]</sup>.</p><p>The Adenosine Triphosphate test is used for preventing viral infections in the healthcare and food sectors. Since ATP is found in every living organism, its presence indicates if there is any biological material present on a surface. In a food safety lab, it is being tested using a detector called a Luminometer.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241011/1728617773664394.png" title="" alt="2.png"/></p><p style="text-align: center;"><em><span style="font-size: 12px;">Public domain image from:&nbsp;https://en.wikipedia.org/wiki/Adenosine_triphosphate</span></em></p><p><strong>Pathogenic Bacteria Rendering Food Safety</strong></p><p>The main reason for spoiled or unhygienic food is the presence of pathogens in it. As time passes, bacteria, fungi, and other microorganisms multiply on the surface of food, making it unsafe for consumption.</p><p>Due to certain environmental conditions, pH, and temperature levels, these pathogens continue to grow. For instance, bacteria grow in huge numbers at 37 °C, which is the room temperature in many regions. That’s why it is the first microbe to be grown on food.</p><p>Here are some of the most common foodborne pathogens:</p><p><strong>1. Salmonella</strong></p><ul style="list-style-type: disc;"><li><p><strong>Potential Period:</strong> Patients get symptoms within 8 to 72 hours after exposure<sup>[3]</sup>.</p></li><li><p><strong>Potential Risks:</strong> Salmonella&nbsp;causes salmonellosis or salmonella infection, leading to upset stomach, diarrhea, fever, and pain.</p></li><li><p><strong>Infectious Dose:&nbsp;</strong>103&nbsp;bacilli (non-typhoidal) and &nbsp;105&nbsp;bacilli (enteric)<sup>[4]</sup>.</p></li></ul><p><strong>2. Listeria Monocytogenes</strong></p><ul style="list-style-type: disc;"><li><p><strong>Potential Period: </strong>Symptoms appear after a few hours, or it may take 2-3 days.</p></li><li><p><strong>Potential Risks: </strong>Causes listeriosis, leading to muscle aches, nausea, stiffness in the neck, headaches, and stomach pain.</p></li><li><p><strong>Infectious Dose:</strong> 10 to 100 million CFU(healthy hosts), and 0.1 to 10 million CFU(&nbsp;individuals at high risk of infection)<sup>[5]</sup>.</p></li></ul><p><strong>3. Vibrio Parahaemolyticus</strong></p><ul style="list-style-type: disc;"><li><p><strong>Potential Period:</strong> Symptoms typically appear 6 hours to 4 days after ingestion<sup>[6]</sup>.</p></li><li><p><strong>Potential Risks:</strong> It is usually caused by eating contaminated seafood. The disease causes watery diarrhea, often with abdominal cramping, nausea, vomiting, fever, and chills.</p></li><li><p><strong>Infectious Dose:</strong> 107 to 108 organisms<sup>[7]</sup></p></li></ul><p><strong>4. Bacillus Cereus</strong></p><ul style="list-style-type: disc;"><li><p><strong>Potential Period:</strong> It usually takes 1-6 hours after ingestion to show symptoms<sup>[8]</sup>.</p></li><li><p><strong>Potential Risks:</strong>&nbsp;Causes nausea, vomiting, abdominal cramps and diarrhea.</p></li><li><p><strong>Infectious Dose:</strong> 104-109&nbsp;cells per gram of food(diarrheal type) and105-108&nbsp;cells per gram of food(emetic type)<sup> [9]</sup>.</p></li></ul><p><strong>5. Clostridium Botulinum</strong></p><ul style="list-style-type: disc;"><li><p><strong>Potential Period:</strong> Symptoms generally appear 12-36 hours after exposure.</p></li><li><p><strong>Potential Risks: </strong>Causes botulism, a rare but serious illness that can lead to marked fatigue, weakness, and vertigo, usually followed by blurred vision, dry mouth, and difficulty in swallowing and speaking. Sometimes, it may lead to respiratory failure and paralysis.</p></li><li><p><strong>Infectious Dose: </strong>Estimated lethal&nbsp;dose is 1.3-2.1&nbsp;ng/kg in humans<sup>[10]</sup>.</p></li></ul><p><br/></p><p><strong>Significance of ATP Monitoring for Microorganism Detection in Food Safety Lab</strong></p><p>ATP monitoring is the ultimate test that is used for microorganism detection in a food safety lab. It is extremely useful to ensure food safety and optimum health conditions. By detecting the presence of ATP on surfaces, food safety professionals can quickly identify areas that may be contaminated with organic matter or microbial growth. And unlike traditional microbiological testing, ATP monitoring provides real-time results, enabling rapid decision-making and proactive measures to maintain a hygienic environment.</p><p><br/></p><p><strong>Tianlong&#39;s Biolum Portable ATP Monitoring System Pro</strong></p><p style="text-align: center;"><strong><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20241017/1729148620880241.jpg" title="" alt="3.jpg"/></strong></p><p>Our Tianlong’s Biolum Portable ATP Monitoring System Pro&nbsp;is a robust tool designed for accurate hygiene monitoring in a food safety lab.</p><p>It provides rapid sanitation verification within 10 seconds&nbsp;of testing. You can easily use the device and can detect 10-16 mol of ATP present on a surface. With a 5-inch shatter-proof touchscreen, easy-to-use UI, and USB-C port for convenient charging, Biolum Pro has made its mark in food safety insurance.&nbsp;</p><p><br/></p><p><strong>Conclusion</strong></p><p>Tianlong&nbsp;is an R&amp;D company that introduced the Biolum Portable ATP Monitoring System, which provides rapid and accurate results. We have&nbsp;been accredited with certifications from&nbsp;the prestigious AOAC Research Institute. Choose Tialong for high-quality and efficient instruments to ensure hygiene in the food safety lab!</p><p>References</p><p>[1]&nbsp;Food safety. Available at: https://www.who.int/news-room/fact-sheets/detail/food-safety (Accessed: 2th, August)</p><p>[2]&nbsp;Respiratory Chain and ATP Synthase. Available at: https://www.sciencedirect.com/topics/neuroscience/atp-synthase (Accessed: 2th, August)</p><p>[3]&nbsp;Salmonella infection. Available at: https://www.mayoclinic.org/diseases-conditions/salmonella/symptoms-causes/syc-20355329 (Accessed: 2th, August)</p><p>[4]&nbsp;Pathogen Safety Data Sheets: Infectious Substances – Salmonella enterica spp.&nbsp;Available at: https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/salmonella-enterica.html (Accessed: 2th, August)</p><p>[5]&nbsp;Listeria monocytogenes: Infectious substances Pathogen Safety Data Sheet. Available at: https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/listeria-monocytogenes.html (Accessed: 2th, August)</p><p>[6]&nbsp;Vibrio parahaemolyticus. Available at: https://www.sciencedirect.com/topics/medicine-and-dentistry/vibrio-parahaemolyticus (Accessed: 2th, August)</p><p>[7]&nbsp;Vibrio Parahaemolyticus. Available at: https://www.ehs.com/resources/sds-resources/free-safety-data-sheet-index/vibrio-parahaemolyticus/ (Accessed: 2th, August)</p><p>[8]&nbsp;Preventing Foodborne Illness: Bacillus cereus. Available at: https://www.nifa.usda.gov/sites/default/files/resource/Preventing-Foodborne-Illness-Bacillus-cereus.pdf (Accessed: 2th, August)</p><p>[9]&nbsp;Bacillus cereus, excluding biovar anthracis: Infectious substances pathogen safety data sheet. Available at: https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/bacillus-cereus.html (Accessed: 2th, August)</p><p>[10]&nbsp;Clostridium botulinum. Available at: https://en.wikipedia.org/wiki/Clostridium_botulinum (Accessed: 2th, August)</p>"
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